BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC50s are 31 nM, 24 nM, 18 nM, 15 nM, respectively.
Specificity:
Target:Ribosomal S6 Kinase (RSK). Fields: BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC50s
Source:
Rabbit
Dilution:
WB 1:500-2000
Concentration:
>98%
Storage Stability:
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
Other Name:
BID1870
MolecularWeight(Da):
391.42
References:
[1]. Sapkota GP, et al. BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J. 2007 Jan 1;401(1):29-38.[2]. Ciceri P, et al. Dual kinase-bromo