商品介绍
Acetyl Lysine Monoclonal Antibody(10B10)
- Catalog No.：YM3449
- Applications：WB,IHC-p,IF(paraffin section)
- Reactivity：Species independent
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Immunogen：
- Purified Protein
- Specificity：
- The antibody detects endogenous Acetyl Lysine protein.
- Formulation：
- PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- Source：
- Mouse
- Dilution：
- WB: 1:1000-2000 IHC: 1:200-500
- Purification：
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- Storage Stability：
- -20°C/1 year
- Background：
- Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis. Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport. The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases , and HDACs have become promising targets for anti-cancer drugs currently in development.
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western blot analysis of 1) Mouse Brain Tissue, 2) Hela, 3) Hela+TSA Treated using Acetyl Lysine Monoclonal Antibody.
- Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using Acetyl Lysine Monoclonal Antibody.
品牌介绍
Immunoway是一家刚成立不就的美国公司，公司位于美国德克萨斯州。主要致力于免疫途径生物技术，开发高质量的ELISA试剂盒、代谢分析试剂盒、与癌症、凋亡、细胞生长和信号转导有关的抗体和抗体/蛋白微阵列方面一直处于领先地位。公司目标是帮助世界各地的生命科学研究人员简化和加速他们的研究与更好的产品和服务。
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