商品介绍
APC5 Polyclonal Antibody
- Catalog No.：YT0262
- Applications：WB,ELISA
- Reactivity：Human
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- ANAPC5
- Protein Name：
- Anaphase-promoting complex subunit 5
- Human Gene Id：
- 51433
- Human Swiss Prot No：
- Q9UJX4
- Mouse Swiss Prot No：
- Q8BTZ4
- Immunogen：
- The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
- Specificity：
- APC5 Polyclonal Antibody detects endogenous levels of APC5 protein.
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
- Purification：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
- MolecularWeight(Da)：
- 85077
- Observed Band(KD)：
- 85
- Background：
- anaphase promoting complex subunit 5(ANAPC5)Homo sapiensThis gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],
- Function：
- function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the APC5 family.,similarity:Contains 4 TPR repeats.,subunit:The APC/C is composed of at least 11 subunits.,
- Subcellular Location：
- nucleus,nucleoplasm,anaphase-promoting complex,cytosol,
- Expression：
- Brain,Cerebellum,Cervix,Epithelium,Lung,Oesophagus,Periodontal liga
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using APC5 Polyclonal Antibody
- Western blot analysis of the lysates from HeLa cells using ANAPC5 antibody.
品牌介绍
Immunoway是一家刚成立不就的美国公司，公司位于美国德克萨斯州。主要致力于免疫途径生物技术，开发高质量的ELISA试剂盒、代谢分析试剂盒、与癌症、凋亡、细胞生长和信号转导有关的抗体和抗体/蛋白微阵列方面一直处于领先地位。公司目标是帮助世界各地的生命科学研究人员简化和加速他们的研究与更好的产品和服务。
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