商品介绍
Cdx2 Polyclonal Antibody
- Catalog No.：YT5817
- Applications：WB,ELISA
- Reactivity：Human,Rat
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- CDX2 CDX3
- Protein Name：
- caudal type homeobox 2
- Human Gene Id：
- 1045
- Human Swiss Prot No：
- Q99626
- Mouse Gene Id：
- 12591
- Mouse Swiss Prot No：
- P43241
- Immunogen：
- Synthetic peptide from human protein at AA range: 201-250
- Specificity：
- The antibody detects endogenous Cdx2 protein
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- WB 1:500-2000, ELISA 1:10000-20000
- Purification：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- CDX2 CDX3
- MolecularWeight(Da)：
- 33520
- Observed Band(KD)：
- 35
- Background：
- caudal type homeobox 2(CDX2)Homo sapiensThis gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012],
- Function：
- function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
- Subcellular Location：
- condensed nuclear chromosome,nucleus,nucleoplasm,transcriptional repressor complex,protein complex,
- Expression：
- Colon,Colon carcinoma,
- June 19-2018
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- FLOW-CYTOMEYRT-PROTOCOL
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- Antibody-FAQs
- Products Images
- Western Blot analysis of MOUSE-BRIAN cells using Antibody diluted at 2000. Secondary antibody(catalog#：RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
品牌介绍
Immunoway是一家刚成立不就的美国公司，公司位于美国德克萨斯州。主要致力于免疫途径生物技术，开发高质量的ELISA试剂盒、代谢分析试剂盒、与癌症、凋亡、细胞生长和信号转导有关的抗体和抗体/蛋白微阵列方面一直处于领先地位。公司目标是帮助世界各地的生命科学研究人员简化和加速他们的研究与更好的产品和服务。
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